Ying Xu
Head of Analytical Sciences Souffle Therapeutics
Seminars
Wednesday 19th August 2026
Analytical Strategies for Oligonucleotide Conjugates: Overcoming Heterogeneity to Enable IND Readiness
12:00 pm
- Addressing conjugation-driven heterogeneity and complexity in oligonucleotide conjugates to enable robust characterization and control
- Defining and controlling critical quality attributes (CQAs) such as DAR, linkage stability, and payload distribution to support IND readiness
- Designing scalable analytical strategies across internal teams and CDMOs to ensure consistent characterization through development and tech transfer
