Paul Peng
Vice President - Chemistry, Manufacturing & Controls City Therapeutics
Seminars
Tuesday 18th August 2026
Fireside Chat: Evaluating Solid-Phase, Enzymatic, & Liquid-Phase Synthesis Routes to Enable Scalable & Sustainable Oligonucleotide Production
9:30 am
- Comparing yield efficiency, impurity formation profiles, and sequence-length constraints across different phase oligo platforms
- Assessing platform readiness for GMP control, stereochemical management, and regulatory acceptance when introducing alternative synthesis technologies
- Determining when transitioning synthesis routes materially improves long-term scalability and manufacturing flexibility
