John Marino

Company: National Institute of Standards & Technology (NIST)

Job title: IBBR Co-Director

Seminars:

2:30 pm Part 2 – Emerging Technologies: Innovative Analytical Development and Harmonization for Oligonucleotide Drugs 2:30 pm - 4:30 pm

An overview of NIST’s measurement and standards program area for oligonucleotides therapeutics, from short oligos to mRNA HOS techniques: NMR, cryoEM and small angle scattering methods for structure and morphology assessment Technology case study: NMR as a multi-attribute method for assessment of siRNA and antisense oligonucleotides Harmonization case study: translation of NMR methods into a…Read more

day: Pre-Conference Day

1:00 pm Part 1 – Breaking Boundaries: Innovative Analytical Development for Oligonucleotide-Conjugates 1:00 pm - 2:00 pm

How can we ensure high quality oligonucleotide products are produced as we increase chemistry complexities? This workshop will convene experts to discuss: Discussing other factors of consideration: impurity profile, linkers and conjugation moieties Examining conjugation site analysis and heterogeneities and what methods and equipment can bridge the gap from more traditional oligos Quantifying conjugation and…Read more

day: Pre-Conference Day