Benjamin Rogers

Company: Denali Therapeutics Inc.

Job title: Associate Director/Principal Scientist, Oligonucleotide and Small Molecule CMC

Seminars:

Analytical Strategies for Oligonucleotide Impurity Monitoring & Control in Oligonucleotide Conjugates 2:00 pm

Exploring the key challenges in the characterization and control of oligonucleotide protein transport vehicle (OTV) conjugates These challenges include the masking of protein charge variant profiles by the highly negative charge of the oligonucleotide and the fate and criticality of oligonucleotide impurities during conjugation Additionally, the unique considerations for residual payload assays compared to antibody-small…Read more

day: Day One PM