Implementing Ultrafiltration/Diafiltration for Processing ASOs to Improve Efficiency

Time: 3:00 pm
day: Day 2


  • Examining the capabilities and limitations of UF/DF membranes to process oligonucleotides using antisense oligonucleotides (ASOs) as a model.
  • Investigating the effectiveness of UF/DF in ASO purification processing to concentrate and formulate a liquid drug substance or to prepare an ASO product for lyophilization resulting in a solid API.