2:30 pm Part 2 – Emerging Technologies: Innovative Analytical Development and Harmonization for Oligonucleotide Drugs
Time: 2:30 pm - 4:30 pm
day: Pre-Conference Day
Details:
- An overview of NIST’s measurement and standards program area for oligonucleotides therapeutics, from short oligos to mRNA
- HOS techniques: NMR, cryoEM and small angle scattering methods for structure and morphology assessment
- Technology case study: NMR as a multi-attribute method for assessment of siRNA and antisense oligonucleotides
- Harmonization case study: translation of NMR methods into a pharmaceutical setting
