Development of an AEX Method for the Analysis of the Diastereomers in Oligonucleotide
Time: 9:30 am
day: Day Two AM
Details:
• Case study exploring how a series of oligonucleotide 4 and 5 base shortmers were
evaluated for their diastereomer profile using a Strong Anion Exchange method
• Exploring how the development of the method evaluated a variety of parameters
including temperature, pH, MP buffer type and concentration