Development of AEX & HILIC as Orthogonal Separation Methods to IPRP for the Characterization of Purity & Impurities in Oligonucleotide Products to Ensure Quality

Time: 4:00 pm
day: Day 1


  • Exploring novel chromatography protocols to improve separation and purification in CMC
  • Finding the right methods to separate nucleotides with minimal damage that maintains yield integrity
  • Establishing quantity and quality of oligonucleotides within a drug product for continuous quality control and process monitoring