Separation of PS Diastereomers in GalNAc-Conjugated siRNA by IPRP, HILIC & AEX
Time: 11:30 am
day: Day 1
Details:
- Outlining the CMC & Regulatory perspective on a stereochemical control strategy
- Comparing AEX, IPRP and HILIC chromatography regarding the ability to separate PS diastereomers
- Elaborating on aspects of method development and qualification as well as batch comparison